Active Pharmaceutical Ingredients
Product Introduction
Nicotinamide adenine dinucleotide sodium salt can be prepared by yeast fermentation, purification, and crystallization steps. Specifically, by first growing microorganisms such as S. cerevisiae in the appropriate medium, then the fermentation products are collected and enzymatically processed and purified, and finally crystallized to obtain the final product.
An important coenzyme in the human redox reaction appears in many metabolic reactions of cells. As an essential coenzyme for biocatalysis reactions, it participates in thousands of physiological reactions, such as cell tricarboxylic acid cycle (TCA), fat β oxidation, etc., which is of great significance in the metabolic utilization process of sugar, fat, amino acids and other nutrients. And Chemicalbook is also the sole substrate for a coenzyme I-consuming enzyme (such as a NAD + -dependent ADP ribosyltransferase). Such enzymes decompose coenzyme I (NAD +) as a substrate into ADP ribose and nicotinamide (Nam), which play different physiological functions in different cells, such as DNA repair, cell oxidative pressure regulation and other physiological functions.
Product Feature
1. Redox activity
Nicotinamide adenine dinucleotide sodium salt plays an important role in the energy metabolism of cells, which is a coenzyme in various redox reactions in an organism. It can promote enzymatic activity during cellular respiration and participate in the metabolism of glucose and fat.
β -Nicotinamide adenine dinucleotide (NAD +) and β -reduced nicotinamide adenine dinucleotide (NADH) constitute a coenzyme redox pair (NAD +: NADH), involved in a wide range of enzymatically catalyzed redox reactions. In addition, in the redox reaction, NAD + / NADH is the ADP-nuclease unit donor in the ADP ribolation (ADP-ribosyltransferase; poly (ADP-nuclease) polymerase) reaction.
2.High biological activity
Nicotinamide adenine dinucleotide sodium salt is a compound with high biological activity and is often used in biochemical and cell biology studies.
3. safe and non-toxic
Nicotinamide adenine dinucleotide sodium salts are considered relatively safe compounds, with no reports of any serious toxicity or harm reported. Follow routine laboratory safety procedures during laboratory operation to avoid inhalation, ingestion or contact with skin. Personal protective equipment such as experimental gloves and safety glasses should be used if required. Storage should be kept in dry, low temperature, light conditions, away from combustible and oxidants.
Product Data Sheets
| Analysis | Description | Test Method |
| Appearance | White to yellowish powder | Confirm |
| Identification | Conform to the RT of Standard | Conform |
| Solubility | Easily soluble in water | Conform |
| Purity (% HPLC) | NLT 98 | 98.3 |
| Water content (% by K.F) | NMT 5 | 4. 11 |
| PH | 7.0- 10.0 | 7.6 |
| Sodium Content (% by K.F) | 5.5-7.5 | Conform |
| Arsenic | NLT 0.5 | ND |
| Total microbial count（CFU/g) | NMT 750 | Conform |
| Assay | NLT 98 | 98.2 |
| E.Coli（MPN/g) | NMT 0.2 | ND |
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