What is L-proline?

L-proline is pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. It has a role as a micronutrient, a nutraceutical, an algal metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite and a member of compatible osmolytes. It is a glutamine family amino acid, a proteinogenic amino acid, a proline and a L-alpha-amino acid. It is a conjugate base of a L-prolinium. It is a conjugate acid of a L-prolinate. It is an enantiomer of a D-proline. It is a tautomer of a L-proline zwitterion.

L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond. Proline is a non-essential amino acid that is synthesized from glutamic acid. It is an essential component of collagen and is important for proper functioning of joints and tendons.

Health Benefits of L-proline  

Proline is like a superhero to your body! It helps to keep the skin, joints, and muscles strong and healthy. When you have enough proline in it, it works behind the scenes, repairing the tissue and promoting good digestion. This nutrient interacts with the collagen in our body, and the collagen is like a glue that sticks everything together. Proline plays a key role in building this important protein, helping to maintain skin firmness and joint elasticity. Adequate proline helps improve joint health and improve diseases such as arthritis. It also contributes to the overall cardiovascular function and is beneficial to the heart and other organs. In short: the more proline, the stronger the body parts! Therefore, make sure that you consume enough of this amazing nutrient for better overall health.

Sources of L-proline   

Proline is derived from protein-rich foods such as meat, dairy products, eggs and some plant sources.

L-proline Supplements

For biochemical research, for medicine for malnutrition, protein deficiency, gastrointestinal diseases, scald and postoperative protein supplementation. Amino acid drugs. It is one of the raw materials of compound amino acid large infusion, which is used for malnutrition, protein deficiency, serious gastrointestinal diseases, scald and protein supplement after surgery.accessory substance. Flavor agent, amino-group reaction with sugar, can produce special flavor substances. Used for amino acid injection, compound amino acid infusion, food additives, nutritional supplement solution and other pharmaceutical raw materials and food additives.

Research on L-proline   

There are two ways in proline. First, by direct fermentation method, L-proline was obtained by using glucose and yellow or corynebacterium glutamicum by microbial fermentation; second, by chemical synthesis method, esterification with glutamate and absolute ethanol, and triethanolamine was added to free the amino sulfate, producing glutamate- δ -ethyl ester. Then the metal reducing agent potassium borohydride is used to reduce glutamate- δ -ethyl ester, produce crude proline, and finally the separation and purification of crude proline can produce crude proline.

Conclusion

L-proline (proline for short) is one of the twenty amino acids of human protein synthesis, at room temperature, colorless to white crystal or crystalline powder, smelly, slightly sweet, soluble in water and ethanol, insoluble in diethyl ether, butanol and isopropanol, soluble in inorganic acids. Amino acids are a general term for a class of organic compounds containing amino groups and carboxyl groups. The existence of amino acids in the human body not only provides an important raw material for the synthesis of proteins, but also provides a material basis for promoting growth, conducting normal metabolism and maintaining life.

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