Chiyambi cha Zamalonda
- Spermidine, yomwe imadziwikanso kuti spermidine trihydrochloride, ndi polyamine. Amagawidwa kwambiri mu zamoyo ndipo amapangidwa kuchokera ku putrescine (butanediamine) ndi adenosylmethionine. Spermidine imatha kuletsa neuronal synthase, kumanga ndi kutulutsa DNA; itha kugwiritsidwanso ntchito kuyeretsa mapuloteni omanga DNA ndikulimbikitsa ntchito ya T4 polynucleotide kinase. Pa September 1, 2013, asayansi ochokera ku Germany ndi Austria anachita kafukufuku mogwirizana ndipo ananena kuti umuna ungalepheretse kudwala matenda a Alzheimer.
Njira Yogwirira ntchito
Ntchito Zogulitsa
- Spermidine imatha kuchedwetsa ukalamba wa mapuloteni. Chifukwa mapuloteni amitundu yolemetsa ya mamolekyu amatha kukhala ndi magawo osiyanasiyana pakupanga ma senescence, mapuloteni ena akuluakulu olemera atha kukhala ndi gawo lalikulu pakuwongolera momwe masamba amawonekera. Mapuloteniwa akayamba kuwonongeka, senescence imakhala yosapeŵeka, ndipo zimakhala zovuta kulamulira kuwonongeka kwa mapuloteniwa. Zingathe kuchedwetsa ukalamba. Chifukwa chomwe spermidine imatha kuchedwetsa kukalamba kungakhale kulimbikitsa kaphatikizidwe ka mapuloteniwa kapena kuteteza kuwonongeka kwawo.
Product Application
- Spermidine ndi low molecular weight aliphatic carbide yomwe ili ndi magulu atatu a amine ndipo ndi imodzi mwa ma polyamines achilengedwe omwe amapezeka mu zamoyo zonse. Ndi zofunika zopangira mankhwala kaphatikizidwe ndipo chimagwiritsidwa ntchito mu synthesis wa intermediates mankhwala.Spermidine imakhudzidwa ndi njira zambiri zamoyo zamoyo, monga kulamulira kuchuluka kwa maselo, senescence, chitukuko cha ziwalo, chitetezo cha mthupi, khansa ndi njira zina za thupi ndi zamoyo. Kafukufuku waposachedwa wawonetsa kuti spermidine imagwira ntchito yofunika kwambiri pakuwongolera njira monga synaptic plasticity, oxidative stress, ndi autophagy mu dongosolo lamanjenje.