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Iyini inzuzo ye-nicotinamide?

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Iyini inzuzo ye-nicotinamide?

2024-10-22 14:39:43

I-Niacinamide, eyaziwa nangokuthi i-nicotinamide, iwuhlobo lukavithamini B3 oluthola ukunakwa okukhulu emhlabeni wokunakekelwa kwesikhumba, ezempilo kanye nokuphila kahle. Le vithamini encibilikayo emanzini idlala indima ebalulekile ezinkambisweni ezihlukahlukene zezinto eziphilayo futhi inikeza izinzuzo ezihlukahlukene ezithuthukisa impilo yesikhumba kanye nenhlalakahle jikelele. Kulesi sihloko, sizohlola izinzuzo eziningi ze-niacinamide nokuthi kungani iyisithako esiyisisekelo ezinhlotsheni eziningi zezempilo nezobuhle.

I-Nicotinamide 2

1. Impilo yesikhumba

Enye yezinzuzo ezaziwa kakhulu zei-niacinamideumthelela wayo omkhulu empilweni yesikhumba. Ucwaningo lukhombisa ukuthi i-niacinamide ithuthukisa ukusebenza kwesithiyo sesikhumba, okubalulekile ekugcineni umswakama nokuvikela ezicindezelweni zemvelo. Lokhu kunenzuzo ikakhulukazi kubantu abanesikhumba esomile noma esibucayi, njengoba kusiza ukunciphisa ukulahlekelwa kwamanzi e-transepidermal.

Ukwengeza, i-niacinamide inezinto zokulwa nokuvuvukala ezingadambisa isikhumba esicasukile, ikwenze kube ukukhetha okuhle kulabo abaphethwe yizinduna, i-rosacea, noma i-eczema. Ucwaningo lukhombisa ukuthi ukusetshenziswa kwe-niacinamide ngama-topical kunganciphisa kakhulu izilonda zezinduna futhi kuthuthukise ukuthungwa kwesikhumba sonke.

2. Umphumela wokuguga

Njengoba sikhula, isikhumba sethu sibhekana nezinguquko ezihlukahlukene, kuhlanganise nokulahlekelwa ukunwebeka nokubukeka kwemigqa emihle nemibimbi.I-Niacinamidekukhonjiswe ukuthi ivuselela ukukhiqizwa kwe-collagen, ebalulekile ekugcineni isikhumba siqinile futhi sinwebeka. Ukwengeza, kusiza ukuthuthukisa ithoni yesikhumba futhi kunciphise i-hyperpigmentation yebala elikhulayo, elikhazimulayo.

Ukusetshenziswa njalo kwe-niacinamide emikhiqizweni yokunakekelwa kwesikhumba nakho kungathuthukisa ikhono lesikhumba lokuzilungisa futhi kube nomthelela wokulwa nokuguga. Lokhu kwenza kube isithako esidumile kuma-serum nokhilimu oklanyelwe ukunciphisa izimpawu zokuguga ezibonakalayo.

3. Thuthukisa ukusebenza kwamaseli

Ngaphezu kwezinzuzo zayo zezihloko,i-nicotinamideidlala indima ebalulekile kumetabolism yamangqamuzana. Ingumanduleli we-nicotinamide adenine dinucleotide (NAD+), i-coenzyme edingekayo ekukhiqizeni amandla ngaphakathi kwamaseli. Ngokusekela amazinga e-NAD+, i-niacinamide ingathuthukisa ukusebenza kwamangqamuzana, ithuthukise imetabolism yamandla, futhi ikhuthaze ubungqabavu bebonke.

Lokhu kusekelwa kwamaselula kubaluleke kakhulu njengoba sikhula, njengoba amazinga e-NAD+ ehla ngokwemvelo, okuholela ekwehleni kwamandla nokwanda kokukhathala. Ukwengeza nge-niacinamide kungasiza ukulwa nale miphumela futhi kukhuthaze indlela yokuphila enomdlandla nekhuthele.

4. Izakhiwo ze-Neuroprotective

Ucwaningo olusafufusa luphakamisai-nicotinamideingase ibe nezakhiwo ze-neuroprotective, iyenze ibe umngane ongaba khona ekulweni nezifo ze-neurodeergenerative. Ucwaningo lubonisa ukuthi i-nicotinamide ingasiza ukuvikela amangqamuzana obuchopho emonakalweni futhi ingase ibambe iqhaza ekuthuthukiseni ukusebenza kwengqondo.

Ngokusekela impilo ye-mitochondrial nokunciphisa ukucindezelwa kwe-oxidative, i-nicotinamide ingasiza ekugcineni ubuchopho buphilile njengoba sikhula, okungenzeka kunciphise ingozi yezifo ezinjenge-Alzheimer's kanye nezinye izinhlobo zokuwohloka komqondo.

5. Sekela impilo ye-metabolic

I-Niacinamide iphinde yaxhunyaniswa nempilo ethuthukisiwe ye-metabolic. Kungasiza ukulawula amazinga kashukela egazini futhi kuthuthukise ukuzwela kwe-insulin, kuzuzise abantu abanesifo sikashukela sohlobo 2 noma abasengozini yalesi sifo. Ngokusekela izinqubo ze-metabolic, i-niacinamide ikhuthaza impilo nokuphila kahle iyonke.

Ekuphetheni

Sekukonke,i-niacinamideisakhi esinamandla esinezinzuzo ezihlukahlukene. Kusukela ekuthuthukiseni impilo yesikhumba kanye nokuhlinzeka ngezinzuzo zokulwa nokuguga kuya ekusekeleni ukusebenza kwamangqamuzana nempilo ye-metabolic, ukuguquguquka kwayo kwenza kube isengezo esibalulekile ekunakekelweni kwesikhumba kanye nezinhlobo zokudla. Kungakhathaliseki ukuthi ubheke ukuthuthukisa ithoni yesikhumba sakho, ukukhulisa amazinga amandla, noma ukusekela impilo yonke, i-niacinamide kufanele icatshangelwe. Njengenjwayelo, ngaphambi kokuqala noma yisiphi isithasiselo esisha noma inqubo yokunakekelwa kwesikhumba, thintana nochwepheshe bezempilo ukuze uqiniseke ukuthi ihlangabezana nezidingo zakho ngazinye.

I-Nicotinamide 2


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