Active Pharmaceutical Ingredients
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Product Introduction
TUDCA stands for tauroursodeoxycholic acid, a bile acid that can be naturally found in the body. Tudca is considered to be a safe and well-tolerated supplement with a range of potential health benefits.It is primarily known for its properties that help protect liver health, reduce inflammation, and promote cell growth. It is believed to work by improving the function of the endoplasmic reticulum, a cellular organelle involved in protein folding and lipid metabolism.
Product Data Sheets
| Analysis | Description | Test Method |
| Appearance | White Powder | Visual |
| Odor | Characteristic | Nasil |
| Identification | Conform with reference sample | HPLC |
| Specific Rotation | +41°~ +47° | CP2020 |
| pH | 1.3-2.3 | CP2020 |
| Moisture Content | ≤ 5.0% | GB5009.3 |
| Sulphated Ash | ≤ 0.1% | GB5009.4 |
| Heavy Metals | ≤ 20 ppm | CP2020 |
| Ursodeoxycholic Acid | ≤ 0.5% | HPLC |
| Taurochenodeoxycholic Acid | ≤ 0.8% | HPLC |
| Other Impurity | ≤ 0.5% | HPLC |
| Total of other Impurity | ≤ 1.0% | HPLC |
| Assay | ≥ 98% | HPLC |
Product Function
1. TUDCA is a liver aid introduced as a supplement by ThermoLife in their product Liver Longer. It looks like a good resource for preventing cholestasis.
2. TUDCA has diminishing apoptotic effects, helping with cardiac function, Huntington's disease, Parkinson's Disease, and stroke. Recently, TUDCA has been found to have protective effects in the eye, especially concerning retinal degenerative disorders.
3. TUDCA is reported to enhance CMA, a cellular waste clearance mechanism that can degrade misfolded proteins and damaged organelles, which may be particularly relevant for neurodegenerative diseases.
4. TUDCA exhibits anti-inflammatory effects by modulating immune responses and suppressing inflammatory cytokines.
Product Application
Pharmaceuticals: TUDCA is being investigated for its potential therapeutic use in treating liver diseases such as cholestatic liver disease, non-alcoholic fatty liver disease (NAFLD), and liver cirrhosis. It's also studied in the context of neurodegeneration, diabetes, and other metabolic disorders.
Cosmetics: Although less common, TUDCA has potential applications in cosmetic science for its ability to protect skin cells from oxidative stress and inflammation, which could translate to anti-aging benefits. Research in this area is emerging.
Product Data Sheets
| Analysis | Description | Test Method |
| Appearance | White Powder | Visual |
| Odor | Characteristic | Nasil |
| Identification | Conform with reference sample | HPLC |
| Specific Rotation | +41°~ +47° | CP2020 |
| pH | 1.3-2.3 | CP2020 |
| Moisture Content | ≤ 5.0% | GB5009.3 |
| Sulphated Ash | ≤ 0.1% | GB5009.4 |
| Heavy Metals | ≤ 20 ppm | CP2020 |
| Ursodeoxycholic Acid | ≤ 0.5% | HPLC |
| Taurochenodeoxycholic Acid | ≤ 0.8% | HPLC |
| Other Impurity | ≤ 0.5% | HPLC |
| Total of other Impurity | ≤ 1.0% | HPLC |
| Assay | ≥ 98% | HPLC |
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