Kayan Kayan Kwalliya
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Menene foda na ceramide?
Foda na Ceramide wani nau'in man fetur ne na halitta da ake samu a fatarmu, kuma suna da matuƙar muhimmanci ga fata. Ceramides sun ƙunshi abubuwa da yawa na lipid, kamar phospholipids, glycolipids, da sphingolipids, da sauransu. Musamman ma, wannan sphingolipid zai iya taimaka wa fata ta riƙe danshi, yana barin fata ta kasance mai danshi da laushi. Sphingolipids na iya sauƙaƙe watsa bayanai tsakanin ƙwayoyin fata, haɓaka haɗin gwiwar ƙwayoyin halitta, da kuma sa fata ta fi lafiya.
Hukumar Kula da Hadurra ta Kasa (COA)
| Bincike | Bayani | Hanyar Gwaji |
| Bayyanar | Foda Fari | Na gani |
| Ƙamshi | Halaye | Yaya |
| Ganowa | Yi daidai da misalin tunani | HPLC |
| Girman raga | Ramin 80 mai wucewa 100% | CP2020 |
| Abubuwan Danshi | ≤ 2.0% | GB5009.3-2016 |
| Karfe Masu Nauyi | ≤ 10 ppm | CP2020 |
| Arsenic (As) | ≤ 1.0 ppm | BS EN ISO17294-2 2016 2016 |
| Gubar (Pb) | ≤ 1.0 ppm | BS EN ISO17294-2 2016 |
| Cadmium(Cd) | ≤ 1.0ppm | BS EN ISO17294-2 2016 |
| Mercury (Hg) | ≤ 1ppm | BS EN ISO17294-2 2016 |
| Jimlar Adadin Faranti | ≤ 10000 cfu/g | ISO 4833- 1:2013 |
| Yis da Mould | ≤ 1000 cfu/g | ISO 21527-2:2008 |
| Escherichia Coli | Babu | ISO 16649-2:2001 |
| Salmonella/25g | Babu | ISO 6579-1:2017 |
| Gwaji | ≥10% | HPLC |
Menene aikin foda ceramide?
1. Tsaftace fata daga shiga
Katangar fata ta ƙunshi shingen jiki, sinadarai, garkuwar jiki da ƙwayoyin cuta, kuma shingen jiki galibi ya ƙunshi stratum corneum da haɗin ƙwayoyin halitta. Lipids na ƙwayoyin halitta da na ƙwayoyin halitta a cikin stratum corneum suna da hannu a cikin "tsarin bangon tubali", kuma lipids na ƙwayoyin halitta galibi sun haɗa da ceramides, fatty acids, da cholesterol. Yanayin amphiphilic na ceramides yana ba da damar lipids na shinge su samar da Layer na lipid na ƙwayoyin halitta, yayin da ƙungiyoyin hydrophilic ɗinsu suna haɓaka ruwa mai yawa a cikin epidermal kuma suna hana asarar ruwa mai yawa a cikin fata.
Ceramidefoda zai iya haɓaka haɗakar filaggrin (FLG), wanda ba wai kawai muhimmin furotin ne na tsari ba, har ma da babban tushen abubuwan da ke haifar da danshi. Monomers na FLG suna polymerize don samar da keratin fakiti, waɗanda ke shiga cikin kiyaye tsari da amincin stratum corneum. Filaggrin yana narkewa zuwa amino acid kyauta da sauran abubuwan da ke haifar da danshi na halitta, gami da urea, sodium pyrrolidinone carboxylate, da lactic acid.
2. Canza sigina
Ceramides na cikin ƙwayoyin halitta na iya aiki a matsayin manzanni na biyu a cikin hanyoyin halittu daban-daban. Ceramides na Messenger suna da asali iri ɗaya da ceramides na ba manzo ba, kuma babu wani bambanci mai mahimmanci a cikin tsarin sinadarai, gami da ceramides na sarkar ω-O-acyl-mai tsayi sosai waɗanda ke keɓance ga epidermis. Duk da haka, yawancin abubuwan da suka fara samar da ceramides na ba manzo ba (glucosylceramide) suna cikin vesicles na lamina kuma ba za su iya shiga cikin cytoplasm kai tsaye don shiga cikin watsa sigina ba.
Baya ga kasancewa muhimman sassan tsarin biofilms, lipids, gami da sphingolipids, ana ƙara gane su a matsayin muhimman masu kula da muhimman hanyoyin ƙwayoyin halitta, gami da autophagy. Autophagy muhimmin tsari ne don kiyaye daidaiton sel da sabuntawa a ƙarƙashin yanayin ilimin halittar jiki da na cututtuka.
3. Tsarin garkuwar fata
Lipids na fata suna taka muhimmiyar rawa wajen daidaita garkuwar jiki da kuma amsawar kumburi. Sphingosine, dihydrosphingosine da phytosphingosine suna da irin waɗannan ayyukan kashe ƙwayoyin cuta akan nau'ikan ƙwayoyin cuta na Gram-positive da Gram-negative, ciki har da Escherichia coli, Fusobacterium nucleatum, Staphylococcus aureus, light Streptococcus, da sauransu. Tarin tushen sphingosine a cikin membrane na ƙwayoyin cuta da kuma haifar da lalacewar tsarin ƙwayoyin cuta yana da alaƙa da shigar da tushen sphingosine cikin membrane na cytoplasmic (kwayoyin cuta na Gram-positive da Gram-negative) da kuma lipids na polar a cikin leaflet na ciki na membrane na waje (kwayoyin cuta na Gram-negative), wanda ke haifar da canjin halayen jiki na membrane na ƙwayoyin cuta da kuma asarar aikin membrane.
Sikarin Chromatography na foda na Ceramides daga masana'anta
Ina zan sayi foda ceramide mai yawa?
Sost Biotech tana samar da kashi 99% na masana'antar foda ceramide na halitta. Za mu iya tabbatar da tsarkin ceramide na jijiyoyi, ta yadda zai iya haɗawa da dabarar ku da kuma yin tasirinsa. Don ƙarin bayani ko tambayoyi, tuntuɓe mu:ericyang@xasost.com.
Takardun Bayanan Samfura
| Bincike | Bayani | Hanyar Gwaji |
| Bayyanar | Foda Mai Rawaya Mai Sauƙi | Na gani |
| Ƙamshi | Halaye | Yaya |
| Ganowa | Yi daidai da misalin tunani | HPLC |
| Girman raga | Ramin 80 mai wucewa 100% | CP2020 |
| Abubuwan Danshi | ≤ 2.0% | GB5009.3-2016 |
| Karfe Masu Nauyi | ≤ 10 ppm | CP2020 |
| Arsenic (As) | ≤ 1.0 ppm | BS EN ISO17294-2 2016 2016 |
| Gubar (Pb) | ≤ 1.0 ppm | BS EN ISO17294-2 2016 |
| Cadmium(Cd) | ≤ 1.0ppm | BS EN ISO17294-2 2016 |
| Mercury (Hg) | ≤ 1ppm | BS EN ISO17294-2 2016 |
| Jimlar Adadin Faranti | ≤ 10000 cfu/g | ISO 4833- 1:2013 |
| Yis da Mould | ≤ 1000 cfu/g | ISO 21527-2:2008 |
| Escherichia Coli | Babu | ISO 16649-2:2001 |
| Salmonella/25g | Babu | ISO 6579-1:2017 |
| Gwaji | ≥10% | HPLC |
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