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Huperzine-A Introduction
Huperzine A is an organic compound with the chemical formula C15H18N2O. It is mainly used as a cholinesterase inhibitor for benign memory disorders in middle-aged and elderly people and various types of dementia, cognitive memory function and emotional and behavioral disorders. It can also be used for Benign memory disorders and various types of dementia, cognitive memory function and emotional and behavioral disorders in middle-aged and elderly people. Treatment of myasthenia gravis.
Huperzine-A 99%, as a potent acetylcholinesterase inhibitor, can easily cross the blood-brain barrier into the central nervous system and bind with acetylcholinesterase, thus inhibiting acetylcholinesterase in the brain, thus reducing the breakdown of acetylcholine, increasing the concentration of acetylcholine inside the brain, and improving the signalling between synapses. It is worth mentioning that this inhibitory effect of sarcosine A is reversible, when the concentration of acetylcholine reaches a certain level, it can be separated from acetylcholinesterase.

Product Data Sheets
Item | Specification | Methods |
Description | Fine powder | Organoleptic |
Color | White powder | Visual |
Assay(%) | NLT 99% | HPLC |
Lost on drying (%) | NMT 5% | 5g / 105℃ /4hrs |
Mesh size | 95% pass 80 mesh | USP<786> |
HEAVY METALS | ≤10.00mg/Kg | USP<231> |
Pb | ≤2.00 mg/Kg | AAS |
As | ≤1.00 mg/Kg | AAS |
Hg | ≤1.00 mg/Kg | AAS |
Cd | ≤1.00 mg/Kg | AAS |
Ash content (%) | NMT 5% | 2g / 525℃ / 3hrs |
Total Bacteria | ≤1000cfu/g | USP30<61> |
Yeast&Mold | ≤100cfu/g | USP30<61> |
Salmonella | Negative | USP30<61> |
E.Coli | Negative | USP30<61> |
Identification | HPLC/UV-VIS/GC | |
Storage | In cool & dry place, keep away from strong light and heat. | |
Remark | Shelf life: Two years when properly stored. |
Product Function
Huperzine A is a new alkaloid isolated from the plant Melaleuca of the genus Melaleuca. It has strong cholinomimetic activity and is a highly efficient and reversible cholinesterase inhibitor. By inhibiting cholinesterase, it inhibits the degradation of acetylcholine and increases its activity, which may improve neurotransmitter transmission. The main side effects are vomiting and constipation.
It is clinically used to treat Alzheimer's disease. Alzheimer's disease is a degenerative disease of the nervous system that mostly occurs in people over 60 years old and has an insidious onset. It can manifest as progressive mental decline and personality changes. There are no specific treatments. Drugs that improve brain metabolism and improve blood circulation can be used in the early stage. Donepezil and Shishanmaine A can also be used.

Scientific administration of huperzine A
1.Pay attention to the dose
The daily dose of huperzine A should not be more than 0.45mg, otherwise it is easy to lead to systemic cholinergic system over-excitement, resulting in dizziness, nausea, vomiting, sweating and other side effects, and in serious cases, even lead to blurred vision, changes in heart rate, salivation and other adverse reactions.
2.Pay attention to adverse reactions
Huperzine A 99% of the conventional dose of adverse reactions are less, but a small number of patients who are sensitive to lithopanax A will appear extrapyramidal reactions, clinical manifestations of tinnitus, dizziness, muscle fasciculations, limb tremor, etc., but most of them can be tolerated, do not need to stop the drug, and there are also patients who will experience abdominal pain, nausea, vomiting, blurred vision and other adverse reactions, which can be reduced the dose of the drug. Severe reactions can be oral atropine to achieve the effect of relief.
3.Pay attention to the mixing of drugs
Clinical treatment of dementia often need to combine a variety of drugs, so in the use of huperzine A should also be combined with nutritive brain cell drugs or improve cerebral circulation drugs, so that multiple perspectives to improve the nutrition and metabolism of the brain cells, and together to promote the improvement of brain function.
✓ Bulk discounts (MOQ 25kg)
✓ FREE 20g samples with COA
✓ OEM services/Specification customization
>>>Click here to get more information
The daily dose of huperzine A should not be more than 0.45mg, otherwise it is easy to lead to systemic cholinergic system over-excitement, resulting in dizziness, nausea, vomiting, sweating and other side effects, and in serious cases, even lead to blurred vision, changes in heart rate, salivation and other adverse reactions.
2.Pay attention to adverse reactions
Huperzine A 99% of the conventional dose of adverse reactions are less, but a small number of patients who are sensitive to lithopanax A will appear extrapyramidal reactions, clinical manifestations of tinnitus, dizziness, muscle fasciculations, limb tremor, etc., but most of them can be tolerated, do not need to stop the drug, and there are also patients who will experience abdominal pain, nausea, vomiting, blurred vision and other adverse reactions, which can be reduced the dose of the drug. Severe reactions can be oral atropine to achieve the effect of relief.
3.Pay attention to the mixing of drugs
Clinical treatment of dementia often need to combine a variety of drugs, so in the use of huperzine A should also be combined with nutritive brain cell drugs or improve cerebral circulation drugs, so that multiple perspectives to improve the nutrition and metabolism of the brain cells, and together to promote the improvement of brain function.
Huperzine A Powder Supplier - Xi'an Sost Biotech
✓ Bulk discounts (MOQ 25kg)
✓ FREE 20g samples with COA
✓ OEM services/Specification customization
>>>Click here to get more information
Product Data Sheets
Item | Specification | Methods |
Description | Fine powder | Organoleptic |
Color | White powder | Visual |
Assay(%) | NLT 99% | HPLC |
Lost on drying (%) | NMT 5% | 5g / 105℃ /4hrs |
Mesh size | 95% pass 80 mesh | USP<786> |
HEAVY METALS | ≤10.00mg/Kg | USP<231> |
Pb | ≤2.00 mg/Kg | AAS |
As | ≤1.00 mg/Kg | AAS |
Hg | ≤1.00 mg/Kg | AAS |
Cd | ≤1.00 mg/Kg | AAS |
Ash content (%) | NMT 5% | 2g / 525℃ / 3hrs |
Total Bacteria | ≤1000cfu/g | USP30<61> |
Yeast&Mold | ≤100cfu/g | USP30<61> |
Salmonella | Negative | USP30<61> |
E.Coli | Negative | USP30<61> |
Identification | HPLC/UV-VIS/GC | |
Storage | In cool & dry place, keep away from strong light and heat. | |
Remark | Shelf life: Two years when properly stored. |
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