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Huperzine-A 99%

Active Pharmaceutical Ingredients

Huperzine-A 99%

Product Name: Huperzine-A
Specifications:  99%
Appearance: white Powder
Test Method: HPLC
Sample: Free Sample
Stock: In Stock
Shelf Life: 2 Years

 

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    Huperzine-A Introduction

    Huperzine A is an organic compound with the chemical formula C15H18N2O. It is mainly used as a cholinesterase inhibitor for benign memory disorders in middle-aged and elderly people and various types of dementia, cognitive memory function and emotional and behavioral disorders. It can also be used for Benign memory disorders and various types of dementia, cognitive memory function and emotional and behavioral disorders in middle-aged and elderly people. Treatment of myasthenia gravis.

    Huperzine-A 99%, as a potent acetylcholinesterase inhibitor, can easily cross the blood-brain barrier into the central nervous system and bind with acetylcholinesterase, thus inhibiting acetylcholinesterase in the brain, thus reducing the breakdown of acetylcholine, increasing the concentration of acetylcholine inside the brain, and improving the signalling between synapses. It is worth mentioning that this inhibitory effect of sarcosine A is reversible, when the concentration of acetylcholine reaches a certain level, it can be separated from acetylcholinesterase.

    Huperzine-A

    Product Data Sheets

    Item  Specification Methods
    Description Fine powder Organoleptic
    Color White powder Visual
    Assay(%) NLT 99% HPLC
    Lost on drying (%) NMT 5% 5g / 105℃ /4hrs
    Mesh size 95% pass 80 mesh USP<786>
    HEAVY METALS ≤10.00mg/Kg USP<231>
    Pb ≤2.00 mg/Kg AAS
    As ≤1.00 mg/Kg AAS
    Hg ≤1.00 mg/Kg AAS
    Cd ≤1.00 mg/Kg AAS
     Ash content (%) NMT 5% 2g / 525℃ / 3hrs
     Total Bacteria ≤1000cfu/g USP30<61>
     Yeast&Mold ≤100cfu/g USP30<61>
     Salmonella  Negative USP30<61>
     E.Coli Negative USP30<61>
    Identification HPLC/UV-VIS/GC
    Storage  In cool & dry place, keep away from strong light and heat.
    Remark Shelf life: Two years when properly stored.

    Product Function

    Huperzine A is a new alkaloid isolated from the plant Melaleuca of the genus Melaleuca. It has strong cholinomimetic activity and is a highly efficient and reversible cholinesterase inhibitor. By inhibiting cholinesterase, it inhibits the degradation of acetylcholine and increases its activity, which may improve neurotransmitter transmission. The main side effects are vomiting and constipation.

    It is clinically used to treat Alzheimer's disease. Alzheimer's disease is a degenerative disease of the nervous system that mostly occurs in people over 60 years old and has an insidious onset. It can manifest as progressive mental decline and personality changes. There are no specific treatments. Drugs that improve brain metabolism and improve blood circulation can be used in the early stage. Donepezil and Shishanmaine A can also be used.
    Huperzine-A powder

    Scientific administration of huperzine A

    1.Pay attention to the dose

    The daily dose of huperzine A should not be more than 0.45mg, otherwise it is easy to lead to systemic cholinergic system over-excitement, resulting in dizziness, nausea, vomiting, sweating and other side effects, and in serious cases, even lead to blurred vision, changes in heart rate, salivation and other adverse reactions.

    2.Pay attention to adverse reactions

    Huperzine A 99% of the conventional dose of adverse reactions are less, but a small number of patients who are sensitive to lithopanax A will appear extrapyramidal reactions, clinical manifestations of tinnitus, dizziness, muscle fasciculations, limb tremor, etc., but most of them can be tolerated, do not need to stop the drug, and there are also patients who will experience abdominal pain, nausea, vomiting, blurred vision and other adverse reactions, which can be reduced the dose of the drug. Severe reactions can be oral atropine to achieve the effect of relief.

    3.Pay attention to the mixing of drugs

    Clinical treatment of dementia often need to combine a variety of drugs, so in the use of huperzine A should also be combined with nutritive brain cell drugs or improve cerebral circulation drugs, so that multiple perspectives to improve the nutrition and metabolism of the brain cells, and together to promote the improvement of brain function.

    Huperzine A Powder Supplier - Xi'an Sost Biotech


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    Product Data Sheets

    Item  Specification Methods
    Description Fine powder Organoleptic
    Color White powder Visual
    Assay(%) NLT 99% HPLC
    Lost on drying (%) NMT 5% 5g / 105℃ /4hrs
    Mesh size 95% pass 80 mesh USP<786>
    HEAVY METALS ≤10.00mg/Kg USP<231>
    Pb ≤2.00 mg/Kg AAS
    As ≤1.00 mg/Kg AAS
    Hg ≤1.00 mg/Kg AAS
    Cd ≤1.00 mg/Kg AAS
     Ash content (%) NMT 5% 2g / 525℃ / 3hrs
     Total Bacteria ≤1000cfu/g USP30<61>
     Yeast&Mold ≤100cfu/g USP30<61>
     Salmonella  Negative USP30<61>
     E.Coli Negative USP30<61>
    Identification HPLC/UV-VIS/GC
    Storage  In cool & dry place, keep away from strong light and heat.
    Remark Shelf life: Two years when properly stored.

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