Usoro Amino Acid
0102030405
Okwu Mmalite Ngwaahịa
A na-ahụ L-threonate nke ọma n'osisi, acid afọ mmadụ na uric acid. Ọ bụ ihe na-emebi emebi nke L-ascorbic acid. Ihe ndị na-acha ọcha, fọrọ nke nta ka ọ bụrụ ihe na-esi ísì na enweghị ụtọ, a na-agbaze na mmiri, a na-agbaze ngwa ngwa na mmiri ọkụ, a naghị agbaze na mmanya, ether na chloroform. Ebe agbaze ahụ dị elu karịa 330℃ (ire ere), ezigbo acid na alkali iguzogide, nkwụsi ike okpomọkụ siri ike, enweghị mgbanwe mgbe a na-ekpo ọkụ na 120℃ maka nkeji 20 ma ọ bụ 200℃ maka nkeji 10. Calcium L-threonate bụ ihe mejupụtara sịntetik eji agwọ nsogbu ọkpụkpụ. L-threonate bụ metabolite na-arụ ọrụ nke sitere na vitamin C ma achọpụtala na ọ na-eme ka nnabata na ojiji nke mineral dị ka calcium dịkwuo mma. Calcium L-threonate bụ ihe dị ike nke na-akwalite nhazi ọkpụkpụ nke ọma ma na-egbochi ọrụ osteoclast.
Mpempe akwụkwọ data ngwaahịa
| Nyocha | Nkọwa | Usoro Ule |
| Ọdịdị | Ntụ ntụ ọcha ma ọ bụ nke fọrọ nke nta ka ọ bụrụ ọcha | Anya na-ahụ anya |
| pH | 6.4 | USP 791 |
| Nchọpụta | Ezi | USP 191 |
| Mgbanwe kpọmkwem | 13.3° | USP781S |
| Mfu mgbe a kpọrọ nkụ | ≤1.0% | USP 731 |
| Mmiri anaghị agbaze agbaze | ≤0.1% | USP 857 |
| Onye ndu | ≤0.5ppm | USP251 |
| Dị ka | ≤1ppm | USP211 |
| Cd | ≤1ppm | USP231 |
| Mercury | ≤0.5ppm | USP261 |
| Nnwale | ≥98.0% | SOP-ZL-114 A/0 |
ọrụ
Calcium L-threonate nwere ike ime ka ọnụego ngosipụta dị mma nke mRNA collagen ụdị nke mbụ dịkwuo elu na chondrocytes na osteoblasts, mee ka ọnụego ngosipụta dị mma nke chondrocytes dịkwuo elu na cartilage articular na epiphyseal cartilage, kwalite uto nke chondrocytes, ma mee ka ọnụọgụ nke collagen ọkpụkpụ dịkwuo elu. , kwalite nhazi ọkpụkpụ, mmepụta matrix cartilage na njikọ proteoglycan, ma nwee ike ịkwalite nhazi nke nri ọkpụkpụ na-edozi ahụ ma melite microcirculation ọkpụkpụ. A na-ahụkarị L-threonate na osisi, acid gastric mmadụ na uric acid. Ọ bụ ngwaahịa mmebi nke L-ascorbic acid. Enwere ike iji Calcium L-threonate dị ka ihe na-eme ka nri sie ike na mgbakwunye calcium.
Njirimara Ngwaahịa
1. Oke mgbaze
E mere nnwale ntụnyere ịgbaze n'etiti calcium threonate na ngwaahịa ndị yiri ya. Calcium threonate nwere obere ọdịnaya calcium ma nwee ike ịgbaze nke ọma karịa ngwaahịa ndị ọzọ yiri ya. Ịgbaze ya na-abawanye ka pH na-ebelata, ọ na-adịkwa ntakịrị alkaline. Ọ ka nwere ezigbo mgbaze n'ebe na-anọpụ iche na gburugburu ebe na-adịghị anọpụ iche. Oke mgbaze nke calcium threonate n'elu oke pH sara mbara bụ ihe dị mkpa nke jikọtara ya na nnukwu mmịpụta. Okpomọkụ enweghị mmetụta dị ukwuu na ịgbaze ya, mgbaze ahụ dịkwa elu karịa na okpomọkụ ụlọ, yabụ calcium threonate dabara adaba dị ka ihe na-eme ka calcium sie ike.
2. Nnukwu nnabata na nnweta nke ihe ndị dị ndụ.
Ihe e ji mara calcium threonate bụ na calcium nke mmadụ na-amịkọrọ na-enweta ike ịmịkọrọ nke ọma. Na mgbakwunye, calcium threonate nwekwara ike ịba uru dị ukwuu dịka ịkwalite nhazi ọkpụkpụ na ibelata oke ọkpụkpụ.
3. Belata ihe mgbochi ndị na-egbochi mmịpụta ígwè
N'ozuzu, calcium na-egbochi ahụ ịnabata mineral ndị ọzọ, mana calcium threonate nwere ike ibelata ihe mgbochi ahụ na-egbochi ịmịkọrọ ígwè. Deehr et al. mụrụ mmetụta calcium na ịmịkọrọ ígwè n'ime ụmụ nwanyị 19 dị afọ 52 ruo 72. Mgbe ndị a riechara nri ụtụtụ nke e tinyere 53 Fe, ndị a rie placebo, mmiri ara ehi nwere 500 mg nke calcium, na mmiri oroma ọhụrụ nwere calcium threonate. Nsonaazụ gosiri na usoro idobe 53 Fe bụ placebo (813%) > mmiri oroma ọhụrụ ejikọtara ya na calcium threonate (714%) > calcium threonate (610%) > mmiri ara ehi (314%), si otú a na-akwado na Calcium threonate nwere ike igbochi * n'ezie.
4. Ezigbo ụtọ
Ihe mgbakwunye calcium na-enyekarị mmadụ ụtọ ọjọọ dịka "siri ike, oseose", mana calcium threonate nwere njirimara nke dị nro, dị nro na ezigbo ụtọ.
5. Nchekwa na anaghị egbu egbu
Calcium threonate bụ calcium nke e ji ihe ndị dị ndụ mee nke ọma n'ihe gbasara nri. Ọ bụ ihe e ji ihe ndị dị ndụ mee nke ọma (GRAS) na mba Amerịka, a pụkwara iji ya mee ihe n'ọtụtụ nri. A nwalere ya n'ọtụtụ ule dị iche iche na nke na-egbu egbu na òké na nnwale iri nri ụbọchị 90 na òké. Nsonaazụ nnwale ahụ gosiri na Calcium threonate anaghị egbu egbu.
Mpempe akwụkwọ data ngwaahịa
| Nyocha | Nkọwa | Usoro Ule |
| Ọdịdị | Ntụ ntụ ọcha ma ọ bụ nke fọrọ nke nta ka ọ bụrụ ọcha | Anya na-ahụ anya |
| pH | 6.4 | USP 791 |
| Nchọpụta | Ezi | USP 191 |
| Mgbanwe kpọmkwem | 13.3° | USP781S |
| Mfu mgbe a kpọrọ nkụ | ≤1.0% | USP 731 |
| Mmiri anaghị agbaze agbaze | ≤0.1% | USP 857 |
| Onye ndu | ≤0.5ppm | USP251 |
| Dị ka | ≤1ppm | USP211 |
| Cd | ≤1ppm | USP231 |
| Mercury | ≤0.5ppm | USP261 |
| Nnwale | ≥98.0% | SOP-ZL-114 A/0 |
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