Paura Hesperidin

Ko te Hesperidin he glycoside dihydroflavonoid me te tātai ngota C29H33O15 me te taumaha ngota o te 610.56. Ko te hesperidin parakore ka puta mai he tioata ma rite ki te ngira, ko te tango mata he paura tioata parauri pouri. I wehea tuatahitia mai i te kiri citrus i te tau 1828, koinei te matū matua o te huaora P (huaora uruhanga), i tapaina ai ko "huaora taiao P". He whānui te horapa o te Hesperidin i roto i te taiao: 30%–50% ka kitea i roto i te kiri, te pericarp me te kiri o ngā hua citrus maroke, ā, tata ki te 1%–5% ka kitea i roto i te kiri. Ko te hanga ahumahi hou e whakamahi ana i ngā para tukatuka hua citrus, ngā kiri me ngā pericarp hei rauemi mata. Mā te tango kawakore me te whakapūmau waikawa, te tango āwhina-ultrasonic, te whakawhiti katote rānei, i kukū te hesperidin ki te neke atu i te 90% kātahi ka whakamarokehia ki roto i te paura hesperidin wai.

Wai: E hiahiatia ana kia 50 rita wai parakore i te 25°C hei whakarewa katoa i te 1 karamu o te paura hesperidin; ka paku piki ake te wairewatanga i roto i te wai wera i runga ake i te 70°C.

Ngā whakarewa rauropi: He wairewa noa i roto i te pyridine, te dimethylformamide me te otinga konutai hauwai; he wairewa paku i roto i te waikawa acetic glacial me te methanol; kāore e wairewa i roto i te acetone, te benzene, te chloroform me te ether.

Te aro ki te pH: I roto i ngā otinga kawakore (pH > 9), ka tuwhera me te mowhiti e hanga ana i a rātou, ka tere ake te whakanui ake i tōna wairewatanga. Ina hoki te pH ki ngā taumata waikawa, ka kati anō ka pupuhi. Nō reira, ko te "whakarewatanga kawakore me te whakapūnga waikawa" he tikanga e whakamahia whānuitia ana mō te purenga o te paura hesperidine i roto i te taiwhanga.

Te Hiranga o te Tukanga: Nā te ngoikore o te wairewatanga ki te wai, ka ngāwari te whakapūpū i te paura hesperidine noa i roto i ngā pūnaha wai nui pērā i ngā inu me ngā wai ā-waha. Ko te whakaurunga o te hydroxypropyl-β-cyclodextrin, te marara totoka, te tikanga microemulsification rānei e whakamahia whānuitia ana i roto i te ahumahi hei whakapai ake i te pumau o tōna marara wai me te whakarite i te parakore me te mārama o te hua whakamutunga.

Nō ngā pūnaha whakaingoa tawhito me ngā pūnaha whakaingoa hou ngā "Glycosides" me ngā "glycosides":
• Ngā ingoa tawhito: Ko "Glycosides" i roto i te hesperidin i whakamāoritia mai i te reo Hapanihi i ngā tau 1950;
• Ingoa hou: Whai muri i te tekau tau atu i 1990, i whakarerekētia e te Komiti Kupu Pūtaiao o tōku whenua te kupu "glycosides" ki te kupu taurite mō te "glycosides", ā, ko te hua o te ingoa ko "hesperidin".

Nō reira, i roto i ngā puka mātauranga, ngā pukapuka rongoā me ngā paerewa o te ao, kua tuhia inaianei ko "hesperidin" i te ara kotahi. Heoi, kei te whakamahi tonu ētahi tuhinga tawhito me ētahi miihini tawhito i te kupu "hesperidin". He rite te hanganga matū me ngā tau CAS o ēnei mea e rua (520-26-3), ā, ka taea te kī he matū kotahi rāua. He mea nui kia mōhio ko ngā kupu "Hesperidin = Hesperidin-7-O-rutinoside" me "Hesperidin = Hesperidin-7-O-neohesperidin" e kitea ana e koe i runga ipurangi he whakamaoritanga hē o "Hesperidin me Neohesperidin" ā, kaua e whakapoauautia.

Mena kei te rapu koe i te paura hesperidine kounga kai, USP rānei, tēnā whakapā atu ki a SOST Biotech, he kaihanga tangohanga tipu ngaio. Kei te rohe hangarau-teitei o Xi'an te tari wheketere. He taiwhanga GMP tōna me ngā taiwhanga whakamātautau HPLC me GC-MS katoa. E toru ngā whakatakotoranga i te nuinga o te wā: 90%, 95%