The Anti-inflammatory Effect of The Turkey Tail Extracts

Benefits of mushrooms after turkey

In Chinese traditional medicine texts, it is called "Yunzhi" (cloud radish); In European and American medical products, it is referred to as "Turkey Tail Extracts." As the name suggests, the turkey tail mushroom (Trametes versicolor) contains two important words: anti-inflammatory properties. According to more than 400 modern studies from around the world, there are three active ingredients: PSK, PSP, and β-glucan.

Prevents chronic inflammation

Chronic inflammation is a major risk factor for atherosclerosis, diabetes, and cancer. Turkey Tail Mushroom Polysaccharide Peptide, PSP, inhibits the NF-κB signaling pathway by inducing cytokines such as TNF-α and IL-6, which alleviate inflammation in general.

It regulates the gut microbiome, not to mention “fighting the fire.”

A recent clinical trial showed that consuming 3600 mg of turkey tail mushrooms daily resulted in an increase in the number of bifidobacteria and lactic acid bacteria in the gut for 8 weeks and a decrease in pathogenic bacteria such as Clostridium . A healthy microbiome environment can further reduce endotoxins in the intestine and reduce the body's inflammatory burden.

Expression of immune cells and cancer support
In the early 1970s, PSK (trade name Krestin) became the dominant treatment for gastric cancer in Japan, with a growth rate of 10% over the next five years. This approach has shown that PSK exerts a potent anti-inflammatory effect on macrophages, T cells, and NK cells, and reduces chemotherapy- and radiotherapy-induced immune cells.

Antibacterial and antibacterial
Studies have shown that turkey tail extract has antiviral activity against Staphylococcus aureus , Salmonella , and influenza viruses. Macrophages have anti-inflammatory and anti-infective effects by enhancing phagocytosis and promoting interferon production.


Other widespread benefits
• Reduces post-exercise inflammation: Rats were found to supplement with 100 mg/kg of Turkey Tail mushroom extract to reduce the levels of CK and LDH. • Improves insulin resistance: The polysaccharide component in CVG increases GLUT4 expression and improves oxidative stress and inflammation.
• Treatment for HPV: After 2 months of oral ingestion of turkey tail mushrooms, 88% of 61 HPV-positive individuals were HPV-positive.

How to Add Egg Tail Mushroom to Supplements? What is the dosage?

Forms of raw material
• Fruit Body Powder: Tough texture, requires boiling in hot water or grinding very finely before use.
• Water/Alcohol Dual Extract: High concentration of active ingredients (polysaccharides and triterpenes), can be dried directly into a powder.
• Standardized Extract: Typical specifications include 10:1 or 20:1, or standardized to 20%-50% polysaccharide, for easy dose control.

Typical dosage forms and compound ratios
• Hard capsules: 400 mg per capsule, available as 100% pure powder or in a ratio of 70% extract + 30% microcrystalline cellulose for easy filling.
• Caramel Press: 30% extract + 60% isomalt + 1% magnesium stearate. 2-3 tablets a day is sufficient.
• Functional beverages: Use 95% cold water soluble polysaccharide powder at a dose of 0.8-1.2 g per bottle, and use cranberry juice concentrate to mask the taste.

Recommended dosage (based on human studies)
• Daily immune support: 1–2 g/day (based on polysaccharides ≥30%).
• Adjuvant cancer therapy: 2-3 g/day, taken in two divided doses with meals; Use with chemotherapy requires medical supervision.
• Anti-inflammatory for athletes: 1.5-2 g/day, taken with water or serum within 30 minutes of exercise.
• Intestinal flora conditioning: 3.6 g/day (PSP 60% purity); Significant changes were seen after 8 weeks.

Combination strategy
• 1:1 combination with Ganoderma lucidum polysaccharides can improve sedation and relieve inflammatory insomnia.

• Supplementing 100 mg of Vitamin C per serving can increase the absorption of polysaccharides by more than 15%.
• Taken with the prebiotic oligofructose (fructooligosaccharide) 3g, it can synergistically promote the growth of bifidobacteria.

Process Notes
• Keep the extraction temperature below 95°C to prevent the long chain of β-glucan from breaking.
• Spray drying inlet air temperature ≤180°C, powder moisture ≤5%, to ensure two-year shelf life.
• Residue testing of heavy metals and pesticides should comply with the limits set in the 2020 edition of the Chinese Pharmacopoeia: lead ≤1.0 ppm, arsenic ≤0.5 ppm.

How to buy？

If you are Turkey Tail Extract buyer, please contact sost biotech or leave a message in our inquiry box.

Email:ericyang@xasost.com