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What is hyaluronic acid good for?

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What is hyaluronic acid good for?

2025-04-15

Hyaluronic acid (HA) has become a fundamental ingredient in modern cosmetic formulations. Cosmetic grade hyaluronic acid is usually produced by microbial fermentation or chemical synthesis, carefully purified to meet stringent safety and quality standards for topical and skin care applications.

 

Hyaluronic acid

 Key benefits of hyaluronic acid for the skin

 

1.Excellent moisturising properties


The main function of hyaluronic acid in cosmetics is its moisturising ability. Typically one gram of hyaluronic acid retains six litres of water, making it an excellent humectant. When applied topically, it forms a moisturising film on the surface of the skin, preventing transepidermal water loss while attracting moisture from the environment.

 

2. Anti-Aging Mechanisms

 

Hyaluronic acid specifications are differentiated by molecular weight. Low molecular weight HA can penetrate the epidermis, stimulate fibroblast activity and promote collagen and elastin synthesis. High molecular weight HA forms a protective barrier on the skin surface, plumping the skin and reducing fine lines.

 

A study in the Journal of Dermatologic Surgery in 2020 showed that topical HA combined with dermal HA injections reduced wrinkle depth by 40% after 12 weeks.

 

3. Enhance skin repair and barrier function

 

Hyaluronic acid plays a crucial role in wound healing and maintaining skin barrier function. It interacts with cell surface receptors, regulates inflammation and promotes epithelial cell migration, thus benefiting sensitive or damaged skin.

 

Products containing HA have been shown to accelerate the recovery of skin irritated by environmental stressors (e.g. UV radiation, pollution) or cosmetic procedures. The US National Library of Medicine (2019) highlights the immunomodulatory effects of HA, which helps to reduce skin redness and improve the skin's natural defence mechanisms.

 

4. Sunscreen and photoprotective adjuvants 

Although HA is not a stand-alone sunscreen, it works synergistically with UV protectants. By enhancing skin hydration, it strengthens the stratum corneum and reduces the penetration of harmful UV rays.

In addition, HA's antioxidant properties help to neutralise free radicals produced by sun exposure, minimising DNA damage and photoaging. Formulations combining HA with zinc oxide or octinoxate showed improved sun protection in preclinical trials (Journal of Cosmetic Dermatology, 2021).

 

How to Use Hyaluronic Acid in Cosmetic Products?
 
Incorporating hyaluronic acid into cosmetic formulations requires understanding its molecular weight variants and compatibility with other ingredients. Here's a guide to effective usage:
Molecular Weight Selection
  • High-Molecular-Weight HA (HMW-HA, >2,000 kDa): Forms a thick film on the skin surface, ideal for moisturizing creams, lotions, and anti-aging serums. Best suited for dry or mature skin types.
  • Low-Molecular-Weight HA (LMW-HA, 10-100 kDa): Penetrates deeper into the dermis, promoting collagen synthesis. Commonly used in serums, ampoules, and anti-wrinkle treatments.
  • Oligomeric HA (oHA, <10 kDa): Exhibits anti-inflammatory and pro-healing effects, suitable for sensitive skin products and post-procedure care.
  • hyaluronic acid into cosmetic

 

Where to Source Cosmetic-Grade Hyaluronic Acid?

 

For formulators and brands, partnering with reliable manufacturers is crucial to ensure product safety and efficacy. Xi'an Sost Biotech stands out as a leading provider of cosmetic-grade hyaluronic acid, offering:
Advanced Production Technology
Using microbial fermentation with genetically optimized Streptococcus strains, Sost Biotech produces HA with consistent molecular weight distribution and low endotoxin levels (<0.1 EU/mg). Their facility adheres to cGMP standards, ensuring batch-to-batch uniformity.
Diverse Product Portfolio
  • Molecular Weight Grades: HMW-HA (1.5-3 MDa), LMW-HA (50-500 kDa), oHA (1-10 kDa), and cross-linked HA for dermal fillers.
  • Formats: Powder (98% purity), liquid solutions (1-10% concentration), and customized blends with natural additives (e.g., aloe vera, hyaluronic acid sodium salt).

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