Mndandanda wa Amino Acid
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Chiyambi cha Zamalonda
L-threonate imapezeka kwambiri mu zomera, asidi wa m'mimba mwa munthu ndi uric acid. Ndi chinthu chochokera ku L-ascorbic acid chomwe chimawonongeka. Tinthu toyera, topanda fungo komanso tokoma, timasungunuka m'madzi, timasungunuka mosavuta m'madzi otentha, sitisungunuka mu mowa, ether ndi chloroform. Kusungunuka kwake kumakhala kokwera kuposa 330℃ (kuwonongeka), asidi wabwino ndi alkali, kutentha kwake kumakhala kolimba, palibe kusintha kulikonse ikatenthedwa pa 120℃ kwa mphindi 20 kapena 200℃ kwa mphindi 10. Calcium L-threonate ndi mankhwala opangidwa omwe amagwiritsidwa ntchito pochiza matenda a mafupa. L-threonate ndi metabolite yogwira ntchito yochokera ku vitamini C ndipo yapezeka kuti imapangitsa kuyamwa ndi kugwiritsa ntchito mchere, monga calcium. Calcium L-threonate ndi mankhwala amphamvu omwe amalimbikitsa bwino mapangidwe a mafupa pamene akuletsa ntchito ya osteoclast.
Mapepala a Deta ya Zamalonda
| Kusanthula | Kufotokozera | Njira Yoyesera |
| Maonekedwe | Ufa woyera kapena pafupifupi woyera | Zooneka |
| pH | 6.4 | USP 791 |
| Kudziwika | Zabwino | USP 191 |
| Kuzungulira kwapadera | 13.3° | USP781S |
| Kutayika pa Kuumitsa | ≤1.0% | USP 731 |
| Madzi osasungunuka | ≤0.1% | USP 857 |
| Mtsogoleri | ≤0.5ppm | USP251 |
| Monga | ≤1ppm | USP211 |
| CD | ≤1ppm | USP231 |
| Mercury | ≤0.5ppm | USP261 |
| Kuyesa | ≥98.0% | SOP-ZL-114 A/0 |
Ntchito
Calcium L-threonate imatha kukulitsa kwambiri kuchuluka kwa collagen mRNA ya mtundu wa I mu ma chondrocyte ndi ma osteoblasts, kukulitsa kwambiri kuchuluka kwa kuwonetsa kwa ma chondrocyte mu articular cartilage ndi epiphyseal cartilage, kulimbikitsa kukula kwa ma chondrocyte, ndikuwonjezera kuchuluka kwa collagen ya mafupa. , imathandizira kupangika kwa mafupa, kupanga ma cartilage matrix ndi kupanga proteoglycan, komanso imathandizira kupangika kwa mitsempha yamagazi ya mafupa ndikuwonjezera kufalikira kwa magazi m'mafupa. L-threonate imapezeka kwambiri mu zomera, asidi wa m'mimba mwa munthu ndi uric acid. Ndi chinthu chowonongeka cha L-ascorbic acid. Calcium L-threonate ingagwiritsidwe ntchito ngati cholimbitsa zakudya komanso chowonjezera calcium.
Mbali ya Zamalonda
1. Kusungunuka kwakukulu
Kuyesa koyerekeza kusungunuka kunachitika pakati pa calcium threonate ndi zinthu zina zofanana. Calcium threonate ili ndi calcium yochepa komanso kusungunuka bwino kuposa zinthu zina zofanana. Kusungunuka kwake kumawonjezeka pamene pH ikuchepa, ndipo ndi yamchere pang'ono. Imakhalabe ndi kusungunuka kwabwino m'malo osalowerera ndale komanso osalowerera ndale. Kusungunuka kwakukulu kwa calcium threonate pa pH yochuluka ndi chinthu chofunikira chomwe chimagwirizana ndi kuyamwa kwambiri. Kutentha sikukhudza kwambiri kusungunuka kwake, ndipo kusungunuka kumakhala kwakukulu pang'ono kutentha kwa chipinda, kotero calcium threonate ndi yoyenera kwambiri ngati cholimbitsa thanzi la calcium.
2. Kuchuluka kwa kuyamwa kwa zinthu zachilengedwe komanso kupezeka kwake.
Khalidwe la calcium threonate ndilakuti calcium yomwe imayamwa m'thupi la munthu imayamwa kwambiri. Kuphatikiza apo, calcium threonate imapezekanso m'thupi monga kulimbikitsa mapangidwe a mafupa ndikuchepetsa kulemera kwa mafupa.
3. Chepetsani zopinga zoyamwa chitsulo
Kawirikawiri, calcium imalepheretsa kuyamwa kwa mchere wina m'thupi, koma calcium threonate imatha kuchepetsa chopinga cha thupi pa kuyamwa kwa chitsulo. Deehr ndi anzake adaphunzira momwe calcium imakhudzira kuyamwa kwa chitsulo mwa akazi 19 azaka zapakati pa 52 ndi 72. Anthuwa atadya chakudya cham'mawa chowonjezera 53 Fe, anthuwa adadya placebo, mkaka wokhala ndi 500 mg ya calcium, ndi madzi a lalanje atsopano okhala ndi calcium threonate. Zotsatira zake zidawonetsa kuti kusungidwa kwa 53 Fe kunali placebo (813%) > madzi a lalanje atsopano ophatikizidwa ndi calcium threonate (714%) > mkaka wa calcium threonate (610%) > mkaka (314%), motero kutsimikizira kuti Calcium threonate imatha * kuletsa.
4. Kukoma kwabwino
Zakudya zowonjezera za calcium nthawi zambiri zimapatsa anthu kukoma koipa monga "kowawa, kokoma", koma calcium threonate imakhala ndi kukoma kokoma, kofewa komanso kwabwino.
5. Yotetezeka komanso yopanda poizoni
Calcium threonate ndi chakudya chotetezeka kwambiri cha calcium. Ndi chakudya chotetezeka (GRAS) ku United States ndipo chingagwiritsidwe ntchito muzakudya zosiyanasiyana. Chayesedwa kwambiri komanso chakupha pa mbewa ndipo chayesedwa kwa masiku 90 pa makoswe. Zotsatira za kafukufukuyu zikusonyeza kuti Calcium threonate si poizoni.
Mapepala a Deta ya Zamalonda
| Kusanthula | Kufotokozera | Njira Yoyesera |
| Maonekedwe | Ufa woyera kapena pafupifupi woyera | Zooneka |
| pH | 6.4 | USP 791 |
| Kudziwika | Zabwino | USP 191 |
| Kuzungulira kwapadera | 13.3° | USP781S |
| Kutayika pa Kuumitsa | ≤1.0% | USP 731 |
| Madzi osasungunuka | ≤0.1% | USP 857 |
| Mtsogoleri | ≤0.5ppm | USP251 |
| Monga | ≤1ppm | USP211 |
| CD | ≤1ppm | USP231 |
| Mercury | ≤0.5ppm | USP261 |
| Kuyesa | ≥98.0% | SOP-ZL-114 A/0 |
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