Active Pharmaceutical Ingredients
what is Pterostilbene Grape Seed Extract?
Pterostilbene grape seed extract , a high-value raw material in the field of plant extracts, is becoming a focal ingredient in the functional food and dietary supplement market. Pterostilbene is a methylated derivative of resveratrol, and its bioavailability is significantly superior to the parent compound. This characteristic gives pterostilbene grape seed extract outstanding potential in antioxidant applications.
From a molecular mechanism perspective, pterostilbene grape seed extract primarily exerts its cytoprotective effects by activating the SIRT1 longevity protein and AMPK signaling pathways. Studies have shown that this component can effectively scavenge free radicals and inhibit lipid peroxidation, with its antioxidant capacity being several times that of vitamin E.
For B2B buyers, understanding this mechanism of action helps in accurately targeting products—whether it's high-end health supplements for the anti-aging market or functional foods for cardiovascular health. Furthermore, the anti-inflammatory, glycemic, and neuroprotective effects of pterostilbene grape seed extract have been supported by numerous preclinical studies, providing a solid scientific foundation for formulation development.
From a molecular mechanism perspective, pterostilbene grape seed extract primarily exerts its cytoprotective effects by activating the SIRT1 longevity protein and AMPK signaling pathways. Studies have shown that this component can effectively scavenge free radicals and inhibit lipid peroxidation, with its antioxidant capacity being several times that of vitamin E.
For B2B buyers, understanding this mechanism of action helps in accurately targeting products—whether it's high-end health supplements for the anti-aging market or functional foods for cardiovascular health. Furthermore, the anti-inflammatory, glycemic, and neuroprotective effects of pterostilbene grape seed extract have been supported by numerous preclinical studies, providing a solid scientific foundation for formulation development.
COA
| Testing Items | Specifications | Method |
| Appearance | off-white or white powder | Visual |
| Melting Point | 92~96°C | Ch.p 2015 II Appendix |
| Assay(HPLC) | >99% | HPLC(liquidoid) |
| Loss on drying | <0.5% | Ch.p 2015II Appendix |
| Moisture Content | <0.5% | GB 5009.3 |
| Karl Fiscoher method | ||
| Ignition Residue | <0.5% | Ch.p 2015II Appendix |
| Heavy Metals | <10ppm | GB 5009.74 |
| Lead(Pb) | ≤5ppm | ISO 17294-2 2016 |
| Arsenic(As) | ≤2ppm | ISO 17294-2 2016 |
| Cadmium(Cd) | ≤2ppm | ISO 17294-2 2016 |
| Mercury(Hg) | ≤1ppm | BS EN 13806:2002 |
pterostilbene's compliance in food/health product development
When applying pterostilbene grape seed extract to end products, compliance is the primary consideration for B2B buyers. Currently, this ingredient can be legally sold as a dietary supplement ingredient in the United States, complying with the FDA's DSHEA regulatory framework; in the EU market, however, attention must be paid to the Novel Food approval status and the scientific opinion of EFSA.
Purchasers are advised to focus on the following compliance points:
*Raw Material Specification Confirmation: Clearly define the pterostilbene content in the pterostilbene grape seed extract (typically 95% or higher purity) to ensure compliance with labeling requirements in the target market.
*Safety Data Support: Obtain toxicological assessment reports and GRAS (Generally Recognized As Safe) documents from the supplier.
*Stability Testing: Verify the shelf-life stability of the raw material in the formulation matrix, particularly its sensitivity to light and temperature.
What are the uses of pterostilbene in cosmetics?
Pterostilbene, a methylated derivative of resveratrol, exhibits remarkable anti-aging properties. A 0.1% concentration of pterostilbene lotion significantly improves skin elasticity and firmness within 28 days, and reduces forehead wrinkles, fine lines around the eyes, and crow's feet.
Pterostilbene powder possesses significant anti-UV damage capabilities, protecting the skin from oxidative stress caused by UVA/UVB radiation.
Pterostilbene has anti-inflammatory properties, soothing sensitive and acne-prone skin.
Pterostilbene powder possesses significant anti-UV damage capabilities, protecting the skin from oxidative stress caused by UVA/UVB radiation.
Pterostilbene has anti-inflammatory properties, soothing sensitive and acne-prone skin.
Production Process and Quality Control Standards for Pterostilbene Grape Seed Extract
The quality of pterostilbene grape seed extract directly depends on the extraction process and quality control system. Currently, the industry mainstream uses supercritical CO₂ extraction combined with chromatographic purification technology. This process effectively preserves the active structure of pterostilbene while avoiding organic solvent residues.
High-quality suppliers should establish the following quality control points:
* Raw Material Traceability Management: Ensure that pesticide residues and heavy metals from grape seeds meet international standards.
* HPLC Detection and Verification: Accurately determine the pterostilbene content using high-performance liquid chromatography; purity typically needs to reach above 95%.
* Microbial Limit Control: Strictly implement USP/EP microbial standards to ensure raw material safety.
* Accelerated Stability Testing: Provide degradation kinetic data under long-term storage conditions.
For bulk purchasers, it is recommended to conduct on-site inspections of the supplier's production facilities to confirm whether they possess ISO, GMP, and other certifications, and whether they have established a full traceability system from raw materials to finished products.
Why Choose SOST Biotech as Your Core Supplier?
Xi'an Sost Biotech Co., Ltd., as a professional manufacturer of plant extracts, has established a significant competitive advantage in the field of pterostilbene grape seed extract. The company possesses standardized extraction workshops and advanced purification equipment, enabling customized production of pterostilbene grape seed extract in multiple specifications, ranging from 95% to 99%, to meet the purity requirements of various application scenarios.
For samples, COA documents, or customized quotations for Pterostilbene Grape Seed Extract, please contact:
Business Email: ericyang@xasost.com
Product Data Sheets
| Testing Items | Specifications | Method |
| Appearance | off-white or white powder | Visual |
| Melting Point | 92~96°C | Ch.p 2015 II Appendix |
| Assay(HPLC) | >99% | HPLC(liquidoid) |
| Loss on drying | <0.5% | Ch.p 2015II Appendix |
| Moisture Content | <0.5% | GB 5009.3 |
| Karl Fiscoher method | ||
| Ignition Residue | <0.5% | Ch.p 2015II Appendix |
| Heavy Metals | <10ppm | GB 5009.74 |
| Lead(Pb) | ≤5ppm | ISO 17294-2 2016 |
| Arsenic(As) | ≤2ppm | ISO 17294-2 2016 |
| Cadmium(Cd) | ≤2ppm | ISO 17294-2 2016 |
| Mercury(Hg) | ≤1ppm | BS EN 13806:2002 |
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