Budada shahwada

Hordhac Badeecada

• Spermidine, oo sidoo kale loo yaqaan spermidine trihydrochloride, waa polyamine. Si ballaaran ayuu ugu faafaa noolaha waxaana laga soo saaraa putrescine (butanediamine) iyo adenosylmethionine. Spermidine wuxuu joojin karaa synthase-ka neerfaha, wuu xidhi karaa oo wuu soo kicin karaa DNA-da; waxaa sidoo kale loo isticmaali karaa in lagu nadiifiyo borotiinnada isku xidha DNA-da iyo in la kiciyo dhaqdhaqaaqa kinase-ka polynucleotide T4. Sebtembar 1, 2013, saynisyahano ka socda Jarmalka iyo Austria ayaa si wadajir ah u sameeyay cilmi-baaris waxayna sheegeen in spermidine uu ka hortagi karo bilowga cudurka Alzheimers.
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Habraaca Shaqada

Hawsha Badeecada

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• Spermidine waxay dib u dhigi kartaa gabowga borotiinka. Sababtoo ah borotiinnada miisaannada molecular ee kala duwan ayaa laga yaabaa inay doorar kala duwan ka ciyaaraan habka gabowga, borotiinnada miisaanka molecular-ka ee waaweyn qaarkood ayaa laga yaabaa inay door muhiim ah ka ciyaaraan xakamaynta habka gabowga caleenta. Marka borotiinnadani ay bilaabaan inay burburaan, gabowga waa lama huraan, waana adag tahay in la xakameeyo burburka borotiinnadan. Waxay dib u dhigi kartaa habka gabowga. Sababta ay spermidine dib u dhigi karto gabowga waxaa laga yaabaa inay tahay in la dhiirrigeliyo isku-darka borotiinnadan ama laga hortago burburkooda.

Codsiga Alaabta

• Spermidine waa aliphatic carbide miisaankiisu hooseeyo oo ka kooban saddex kooxood oo amine ah waana mid ka mid ah polyamine-yada dabiiciga ah ee ku jira dhammaan noolaha. Waa walxo muhiim u ah isku-darka daawada waxaana si weyn loogu isticmaalaa isku-darka daawooyinka dhexdhexaadka ah.

  
  

  Spermidine waxay ku lug leedahay habab badan oo bayooloji ah oo ku jira noolaha, sida nidaaminta taranka unugyada, gabowga unugyada, horumarinta xubnaha, difaaca jirka, kansarka iyo hababka kale ee jir ahaaneed iyo kuwa cudur-sidaha. Daraasado dhowaan la sameeyay ayaa muujiyay in spermidine uu door muhiim ah ka ciyaaro hababka sida plasticity synaptic, walbahaarka oksaydhka, iyo autophagy ee habdhiska neerfaha.
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