Izithako ezisebenzayo zamayeza
Yintoni iFisetin Powder Bulk?
Fisetin powder isambuku yiflavonol yendalo eyaqala yodwa kwizityalo zosapho lwe-Anacardiaceae, kungoko igama layo. I-molecular skeleton yi-polyphenols, kunye ne-chemical formula ye-C₁₅H₁₀O₆, i-CAS No. Ayinyibiliki emanzini, kodwa inyibilika ngokulula kwizinyibilikisi zepolar ezifana ne-acetone, i-ethanol, kunye ne-dimethyl sulfoxide. Ngokwendalo, ukutya okunje ngamaqunube, ii-apile, itswele, iikomkomere, kunye nezikhumba zeediliya zonke ziqulethe umkhondo weFisetin, kodwa isixa sisonke siphantsi kakhulu - abaphengululi baseJapan baye babala ukuba umndilili wokutya okutyiwayo kwemihla ngemihla ngomntu ngamnye malunga ne-0.4 mg kuphela. Ukuba ufuna ukudlala indima ecacileyo kuphando lwezenzululwazi okanye ukutya okusebenzayo, ngokuqhelekileyo ufuna "i-Fisetin powder" ekrwada kunye nokuhlanjululwa kwe-≥98%, efunyenwe ngeenkqubo ezifana nokutsalwa okungcolileyo kwe-Cotinus coggygria okanye i-strawberry, ukucocwa kwe-chromatography, kunye ne-recrystallization, kwaye emva koko ifaneleke nge-HPLC yendlela ephantsi yomgangatho wesicelo ngaphambi kokuba ingene kwiindlela ezisemgangathweni zangaphandle.
I-COA ye-Fisetin Powder eninzi
| Uhlalutyo | Inkcazo | Indlela yoVavanyo |
| Imbonakalo | Umgubo oMthubi | Okubonakalayo |
| Ivumba | Uphawu | I-Organoleptic |
| Ukuchongwa | Qhagamshelana nesampulu yereferensi | I-Organoleptic |
| Ubungakanani beMesh | I-100% iphumelele i-80 mesh | Isikrini se-80mesh |
| Umxholo wokufuma | ≤ 1.0% | GB5009.3-2016 |
| Iintsimbi ezinzima | ≤ 10 ppm | GB 5009.3 |
| IArsenic (As) | ≤ 1.5 ppm | GB 5009.4 |
| Khokela (Pb) | ≤ 2 ppm | GB 5009.11 |
| I-Cadmium (Cd) | ≤1ppm | GB 5009.12 |
| IMercury (Hg) | ≤1ppm | GB 5009.17 |
| Ukubalwa kwePleti iyonke | ≤10000 cfu/g | GB 5009.15 |
| Igwele kunye noMngundo | ≤100 cfu/g | GB 5009.3 |
| Escherichia Coli | GB 5009.4 | |
| Salmonella/25g | Ukungabikho | GB 5009.11 |
| Umgaqo osebenzayo | Fisetin≥98% | HPLC |
Uyintoni umphumo weFisetin powder kwingqondo?
I-Anti-inflammatory kunye ne-immunomodulatory
Enye yeempawu eziqhelekileyo zezifo ze-neurodeergenerative ezifana nesifo se-Alzheimer (AD) kunye nesifo sika-Parkinson (PD) yi-neuroinflammation engapheliyo. I-Fisetin inciphisa ukukhutshwa kwe-cytokines ye-proinflammatory TNF-α, IL-1β, kunye ne-IL-6 ngokuvimbela indlela yokubonisa i-NF-κB, ngaloo ndlela inciphisa "i-second blow" ebangelwa ukusetyenziswa ngokugqithiseleyo kwe-microglia.
Ukukhuthaza i-neuroplasticity
Uvavanyo lwezilwanyana luye lwabonisa ukuba i-Fisetin ingakwazi ukusebenzisa indlela ye-ERK / CREB, ikhulise ukubonakaliswa kweeprotheni ze-synaptic synapsin I kunye ne-PSD95, kunye nokuphucula amandla exesha elide (LTP), ekugqibeleni kubonakalisa ukuphuculwa kokufunda kunye nokukwazi ukudibanisa imemori.
Nciphisa i-β-amyloid deposition
Kwiigundane ze-AD transgenic model, ukulawulwa okuqhubekayo kwe-Fisetin powder 25 mg / kg kwiinyanga ze-3 kunokunciphisa kakhulu indawo ye-Aβ42 plaques kwi-hippocampus kunye nokubuyisela ukulahleka kwememori.
Yenza i-SIRT1 isebenze ixesha elide
I-Fisetin ibonakaliswe ukuba iphakamisa ukubonakaliswa kwe-SIRT1, ukuphucula ukusebenza kwe-mitochondrial, kunye nokulibazisa ukuguga kweeseli. Lo matshini awuhambelani kuphela nokukhusela i-neuroprotection, kodwa kwakhona ithathwa njengento ekujoliswe kuyo entsha yophando oluchasayo.
Kweziphi iindawo enokusetyenziswa kuzo i-fisetin?
Ukutya okusebenzayo/ukutya okukodwa kwezonyango
I-dose ephantsi (≤25 mg / inxalenye) ingasetyenziselwa "njengenkxaso yememori" isithako sefomula kwaye yongezwe kwiibha zamandla kunye neziselo ezilungele ukusela ezisebenzayo.
Izithambiso zokulwa nokuguga
Ukusebenzisa iipropathi zayo ezinamandla ze-antioxidant, i-fisetin powder inokongezwa kwiikhrimu kunye ne-essces ukulwa noxinzelelo lwe-oxidative yesikhumba kunye nokunciphisa i-photoaging.
Iikhompawundi zomgqatswa omtsha weziyobisi
I-derivative CMS121 ene-fisetin njengondoqo womzali isungulwe e-United States kunyango lwe-AD kulingo lweSigaba soku-I kwaye inokungena kwimarike yamayeza amiselweyo kwixesha elizayo.
Ii-reagents zophando lwe-Neuroscience
I-high-purity fisetin powder isetyenziswa ngokubanzi kwiimodeli zoxinzelelo lwe-cell oxidative kunye novavanyo lokuziphatha kwezilwanyana ukufunda iindlela zesifo se-Alzheimer, isifo sika-Parkinson, kunye ne-amyotrophic lateral sclerosis (ALS).
Amayeza eMidlalo
Izifundo zangaphambili zifumene ukuba i-fisetin powder inokulwa ne-encephalopathy engapheliyo (CTE) ebangelwa ukuxhatshazwa ngokuphindaphindiweyo ngokuthintela i-neuroinflammation kunye nokukhuthaza izinto ze-neurotrophic.
Ndingathenga phi ubuninzi befisetin powder? Qhagamshelana ne-SOST
Ukuba ufuna izinto eziluhlaza ze-fisetin powder bulk ezihlangabezana nemigangatho ye-USP / EP kwaye inomxholo we-≥98%, okanye ufuna ukwenza i-OEM/ODM imveliso yelebhile yangasese, unokuqhagamshelana ngokuthe ngqo ne-SOST, umthengisi we-extract plant. I-SOST ineminyaka engaphezu kwe-10 yamava ekuveliseni i-flavonoid monomers, kwaye inokubonelela ngokuzinzile ukusuka kwiigram ukuya kwiitoni, kwaye ixhasa isethi epheleleyo yamaxwebhu okuthotyelwa okufana ne-COA, i-MSDS, kunye neengxelo zovavanyo lomntu wesithathu.
Qhagamshelana nathi IiShethi zeDatha yeMveliso
| Uhlalutyo | Inkcazo | Indlela yoVavanyo |
| Imbonakalo | Umgubo oMthubi | Okubonakalayo |
| Ivumba | Uphawu | I-Organoleptic |
| Ukuchongwa | Qhagamshelana nesampulu yereferensi | I-Organoleptic |
| Ubungakanani beMesh | I-100% iphumelele i-80 mesh | Isikrini se-80mesh |
| Umxholo wokufuma | ≤ 1.0% | GB5009.3-2016 |
| Iintsimbi ezinzima | ≤ 10 ppm | GB 5009.3 |
| IArsenic (As) | ≤ 1.5 ppm | GB 5009.4 |
| Khokela (Pb) | ≤ 2 ppm | GB 5009.11 |
| I-Cadmium (Cd) | ≤1ppm | GB 5009.12 |
| IMercury (Hg) | ≤1ppm | GB 5009.17 |
| Ukubalwa kwePleti iyonke | ≤10000 cfu/g | GB 5009.15 |
| Igwele kunye noMngundo | ≤100 cfu/g | GB 5009.3 |
| Escherichia Coli | GB 5009.4 | |
| Salmonella/25g | Ukungabikho | GB 5009.11 |
| Umgaqo osebenzayo | Fisetin≥98% | HPLC |
Ukupakisha kunye nokuThumela
Yintoni Esinokuyenza?
