Uchungechunge lwe-Amino Acid
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Isingeniso Somkhiqizo
I-L-threonate itholakala kabanzi ezitshalweni, i-asidi yesisu somuntu kanye ne-uric acid. Iwumkhiqizo wokonakala kwe-L-ascorbic acid. Izinhlayiya ezimhlophe, cishe azinaphunga futhi azinambitheki, zincibilika emanzini, zincibilika kalula emanzini ashisayo, azincibiliki otshwaleni, ether kanye ne-chloroform. Indawo yokuncibilika iphakeme kune-330℃ (ukubola), ukumelana okuhle kwe-asidi kanye ne-alkali, ukuqina okuqinile kokushisa, akukho shintsho uma kushiswa ku-120℃ imizuzu engama-20 noma ama-200℃ imizuzu eyi-10. I-Calcium L-threonate iyinhlanganisela yokwenziwa esetshenziselwa ukwelapha izinkinga zamathambo. I-L-threonate iyi-metabolite esebenzayo etholakala ku-vitamin C futhi itholakale ithuthukisa ukumuncwa nokusetshenziswa kwamaminerali, njenge-calcium. I-Calcium L-threonate iyinhlanganisela enamandla ekhuthaza ukwakheka kwamathambo ngempumelelo ngenkathi ivimbela umsebenzi we-osteoclast.
Amashidi Edatha Yomkhiqizo
| Ukuhlaziywa | Incazelo | Indlela Yokuhlola |
| Ukubukeka | Impuphu emhlophe noma ecishe ibe mhlophe | Okubonakalayo |
| i-pH | 6.4 | I-USP 791 |
| Ukuhlonza | Okuhle | I-USP 191 |
| Ukujikeleza okuqondile | 13.3° | I-USP781S |
| Ukulahlekelwa Kokomisa | ≤1.0% | I-USP 731 |
| Amanzi awancibiliki | ≤0.1% | I-USP 857 |
| Umholi | ≤0.5ppm | I-USP251 |
| Njengoba | ≤1ppm | I-USP211 |
| I-CD | ≤1ppm | I-USP231 |
| I-Mercury | ≤0.5ppm | I-USP261 |
| Ukuhlolwa | ≥98.0% | I-SOP-ZL-114 A/0 |
Umsebenzi
I-Calcium L-threonate ingakhuphula kakhulu izinga lokuvezwa okuhle kwe-type I collagen mRNA kuma-chondrocytes nama-osteoblasts, ikhuphule kakhulu izinga lokuvezwa okuhle kwama-chondrocytes ku-articular cartilage kanye ne-epiphyseal cartilage, ikhuthaze ukukhula kwama-chondrocytes, futhi ikhuphule inani le-bone collagen. , ikhuthaza ukwakheka kwamathambo, ukukhiqizwa kwe-cartilage matrix kanye nokwakheka kwe-proteoglycan, futhi ingakhuthaza ukwakheka kwemithambo yegazi yokondla amathambo futhi ithuthukise i-microcirculation yamathambo. I-L-threonate itholakala kabanzi ezitshalweni, i-human gastric acid kanye ne-uric acid. Ingumkhiqizo wokuwohloka kwe-L-ascorbic acid. I-Calcium L-threonate ingasetshenziswa njengesiqiniseko sokudla kanye nesengezo se-calcium.
Isici Somkhiqizo
1. Ukuncibilika okuphezulu
Kwenziwe ukuhlolwa kokuqhathanisa ukuncibilika phakathi kwe-calcium threonate nemikhiqizo efanayo. I-calcium threonate inokuqukethwe kwe-calcium okulingene futhi ukuncibilika kwayo kungcono kakhulu kuneminye imikhiqizo efanayo. Ukuncibilika kwayo kuyanda ngokuncipha kwe-pH, futhi i-alkaline kancane. Isenokuncibilika okuhle ezindaweni ezingathathi hlangothi nezicishe zingathathi hlangothi. Ukuncibilika okuphezulu kwe-calcium threonate ebangeni elikhulu le-pH kuyisici esibalulekile esihlotshaniswa nokumuncwa okuphezulu. Izinga lokushisa alinawo umthelela omkhulu ekuncibilikeni kwayo, futhi ukuncibilika kuphakeme kancane ekushiseni kwegumbi, ngakho-ke i-calcium threonate ifaneleka kakhulu njenge-calcium nutritional forceifier.
2. Ukumuncwa okuphezulu kwezinto eziphilayo kanye nokutholakala kwazo.
Isici se-calcium threonate ukuthi i-calcium emuncwa ngumzimba womuntu inesilinganiso esiphezulu sokumuncwa. Ngaphezu kwalokho, i-calcium threonate nayo inokutholakala okuphezulu kwezinto eziphilayo njengokukhuthaza ukwakheka kwamathambo nokunciphisa ubukhulu bamathambo.
3. Nciphisa izithiyo zokumuncwa kwensimbi
Ngokuvamile, i-calcium iyayivimbela ukumuncwa kwamanye amaminerali emzimbeni, kodwa i-calcium threonate inganciphisa isithiyo somzimba ekumuncweni kwensimbi. UDeehr nabanye bafunde ngomphumela we-calcium ekumuncweni kwensimbi kwabesifazane abangu-19 abaneminyaka engu-52 kuya kwengu-72. Ngemva kokuba labo abathintekayo bedle isidlo sasekuseni esino-53 Fe, labo abathintekayo badle i-placebo, ubisi oluqukethe i-500 mg ye-calcium, kanye nejusi elisha le-orange eliqukethe i-calcium threonate. Imiphumela ibonise ukuthi ukuhleleka kokugcinwa kwe-53 Fe kwakuyi-placebo (813%) > ijusi elisha le-orange elihlanganiswe ne-calcium threonate (714%) > i-calcium threonate (610%) > ubisi (314%), ngaleyo ndlela kuqinisekisa ukuthi i-Calcium threonate ingavimba ngempela.
4. Ukunambitheka okuhle
Izithasiselo ze-calcium zivame ukunikeza abantu ukunambitheka okubi njengokuthi "okungaqinile, okubabayo", kodwa i-calcium threonate inezici zokunambitheka okuthambile, okuthambile nokuhle.
5. Kuphephile futhi akunabo ubuthi
I-calcium threonate iyindlela yokudla ejwayelekile ephephile kakhulu i-calcium. Iyindlela eluhlaza ephephile (i-GRAS) e-United States futhi ingasetshenziswa ekudleni okuhlukahlukene. Ihlolwe kakhulu futhi inobuthi emagundwini kanye nokuhlolwa kokudla kwezinsuku ezingu-90 emagundwini. Imiphumela yokuhlolwa ifakazela ukuthi i-calcium threonate ayinabo ubuthi.
Amashidi Edatha Yomkhiqizo
| Ukuhlaziywa | Incazelo | Indlela Yokuhlola |
| Ukubukeka | Impuphu emhlophe noma ecishe ibe mhlophe | Okubonakalayo |
| i-pH | 6.4 | I-USP 791 |
| Ukuhlonza | Okuhle | I-USP 191 |
| Ukujikeleza okuqondile | 13.3° | I-USP781S |
| Ukulahlekelwa Kokomisa | ≤1.0% | I-USP 731 |
| Amanzi awancibiliki | ≤0.1% | I-USP 857 |
| Umholi | ≤0.5ppm | I-USP251 |
| Njengoba | ≤1ppm | I-USP211 |
| I-CD | ≤1ppm | I-USP231 |
| I-Mercury | ≤0.5ppm | I-USP261 |
| Ukuhlolwa | ≥98.0% | I-SOP-ZL-114 A/0 |
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