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I-Shikonin (i-shikonin, i-shikonin, i-shikonin) iyiklasi yemikhiqizo yemvelo enesakhiwo se-naphthoquinone esikhishwe empandeni ye-Lithospermum officinale, enemiphumela yokulwa nokuvuvukala, i-antioxidant, i-anti-tumor, kanye nokuphulukisa amanxeba. Eminyakeni yamuva nje, imiphumela yokulwa nomdlavuza we-shikonin kanye nemikhiqizo yayo iye yafundwa kabanzi. Izifundo eziningana ze-in vitro kanye ne-in vivo zibonise ukuthi i-shikonin kanye nemikhiqizo yayo ingavimbela ngempumelelo ukwenzeka kanye nokuthuthukiswa kwezifo ezibangelwa amagciwane ezifana nomdlavuza webele kanye nomdlavuza wesibeletho. I-Shikonin inethonya elinamandla lokulwa nomdlavuza ezinhlotsheni ezahlukene zomdlavuza ngokuvimbela ukwanda kwamaseli kanye nokufuduka kwawo, okubangela i-apoptosis yamaseli, i-autophagy kanye ne-necroptosis. I-Shikonin ingaphinde ibangele ukukhiqizwa kwezinhlobo ze-oxygen ezisabelayo (ROS), ivimbele ukukhishwa kwama-exosome, futhi isebenze ukuzivikela kwe-anti-tumor ngokusebenzisa izindlela ezahlukahlukene zama-molecule.